DNAJB9

Across TCGA patient cohorts, DNAJB9 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJB9-associated genes across cancer lineages are ATM, CD49b, and Chk2_pT68. Each is linked with DNAJB9 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJB9-to-partner and partner-to-DNAJB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by DNAJB9-low versus DNAJB9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB9→partner) and Y-score (partner→DNAJB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.674	-3.000	.010	.037	1	1
UCEC	CD49b →	-0.363	-2.986	.027	.037	1	1
UCEC	Chk2_pT68 →	-0.229	-3.000	.033	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ATM by DNAJB9 expression — UCEC

Explore this box plot interactively →