DNAJB9

Across TCGA cell cohorts, DNAJB9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,911 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DNAJB9-associated GO terms across cancer lineages are Response to endoplasmic reticulum stress, ERAD pathway, and Negative regulation of IRE1-mediated unfolded protein response. Each is linked with DNAJB9 in more than 18 cancer types. Because this analysis shows association rather than direction, both DNAJB9-to-partner and partner-to-DNAJB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to endoplasmic reticulum stress grouped by DNAJB9-low versus DNAJB9-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB9→partner) and Y-score (partner→DNAJB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Response to endoplasmic reticulum stress →	+0.088	+1.073	<.001	<.001	3	19
BLOOD_Myeloma	ERAD pathway →	+0.108	+1.883	.002	<.001	3	18
BLOOD_Myeloma	Negative regulation of IRE1-mediated unfolded protein response →	+0.158	+1.724	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Protein exit from endoplasmic reticulum →	+0.126	+0.734	.006	.007	3	17
BLOOD_Myeloma	Negative regulation of endoplasmic reticulum unfolded protein response →	+0.159	+2.010	<.001	<.001	3	15
STOMACH	Endoplasmic reticulum unfolded protein response →	+0.110	+1.290	<.001	<.001	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,911 associations by consensus.

Response to endoplasmic reticulum stress by DNAJB9 expression — BONE

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