DNAJB8-AS1

Across TCGA pan-cancer cohorts, DNAJB8-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated DNAJB8-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher DNAJB8-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DNAJB8-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

UVM, STAD, and KIRC are the cancer types where DNAJB8-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	III,IV	0.105	0.834	<.001	87	view →
STAD	OS	Tertile	III,IV	0.309	0.576	.002	78	view →
KIRC	DFS	Tertile	IV	0.238	0.659	<.001	66	view →
LUSC	OS	Tertile	IV	0.057	0.786	.008	42	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
COAD	DFS	Tertile	III,IV	0.129	0.629	<.001	30	view →
HNSC	OS	Tertile	II,III,IV	0.837	0.648	.014	27	view →
PAAD	OS	Tertile	All	1.000	0.456	.039	18	view →
PCPG	DFS	Median	All	0.929	0.662	.007	15	view →
BLCA	OS	Tertile	IV	0.212	0.582	.026	9	view →
THCA	DFS	Tertile	II,III,IV	0.766	0.912	.037	9	view →
GBM	DFS	Tertile	All	0.313	0.177	.029	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

DNAJB8-AS1–UVM (OS)

Open the UVM breakdown →