DNAJB6P8

Across TCGA pan-cancer cohorts, DNAJB6P8 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of DNAJB6P8’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where DNAJB6P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DNAJB6P8 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

LUAD, BRCA, and HNSC are the cancer types where DNAJB6P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DNAJB6P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.198	.008	6	view →
BRCA	Female	II,III,IV	+0.144	<.001	6	view →
HNSC	All	II,III,IV	+0.030	.024	3	view →
CHOL	Male	All	+0.095	.011	2	view →
KIRP	All	All	−0.048	.014	2	view →
BLCA	Female	IV	+0.103	<.001	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

DNAJB6P8–LUAD

Open the LUAD breakdown →