DNAJB6

Across TCGA patient cohorts, DNAJB6 mutation is significantly associated with the RNA expression of many other genes, with 1,287 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJB6-associated genes across cancer lineages are RNU6-1246P, NENFP2, and MIR7702. Each is linked with DNAJB6 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNAJB6-to-partner and partner-to-DNAJB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1246P grouped by DNAJB6-low versus DNAJB6-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB6→partner) and Y-score (partner→DNAJB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-1246P →	+0.484	+6.763	<.001	<.001	3	3
LIHC	NENFP2 →	+0.072	+4.564	<.001	.006	3	2
UCEC	MIR7702 →	+0.171	+3.812	<.001	.008	3	2
UCEC	NF1P10 →	+0.189	+2.193	<.001	.002	3	2
LIHC	LINC01349 →	+0.229	+3.787	<.001	.009	3	2
LIHC	LINC02032 →	+0.207	+4.720	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,287 associations by consensus.

RNU6-1246P by DNAJB6 expression — HNSC

Explore this box plot interactively →