DNAJB6

Across TCGA cell cohorts, DNAJB6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,028 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJB6-associated GO terms across cancer lineages are Negative regulation of cilium assembly, Regulation of stress-activated protein kinase signaling cascade, and Endoplasmic reticulum-plasma membrane tethering. Each is linked with DNAJB6 in more than 11 cancer types. Because this analysis shows association rather than direction, both DNAJB6-to-partner and partner-to-DNAJB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cilium assembly grouped by DNAJB6-low versus DNAJB6-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB6→partner) and Y-score (partner→DNAJB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of cilium assembly →	+0.074	+0.949	<.001	<.001	3	12
CNS	Regulation of stress-activated protein kinase signaling cascade →	+0.104	+0.778	<.001	<.001	3	11
BREAST	Endoplasmic reticulum-plasma membrane tethering →	+0.155	+0.835	<.001	<.001	3	11
CNS	Vesicle-mediated transport to the plasma membrane →	+0.050	+0.695	.001	.004	3	11
SOFT_TISSUE	Protein depolymerization →	+0.079	+0.633	.003	.007	3	11
LUNG_NSCLC_LUSC	Regulation of isotype switching to IgG isotypes →	+0.125	+1.045	.003	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,028 associations by consensus.

Negative regulation of cilium assembly by DNAJB6 expression — LIVER

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