DNAJB5-DT

Across TCGA pan-cancer cohorts, DNAJB5-DT RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated DNAJB5-DT data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DNAJB5-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DNAJB5-DT expression acts as an unfavorable survival marker, although some lineages such as COAD and PAAD show a favorable association.

LUAD, ACC, and THCA are the cancer types where DNAJB5-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	III,IV	0.148	0.558	<.001	67	view →
ACC	OS	Tertile	III,IV	0.367	0.791	<.001	62	view →
THCA	OS	Tertile	All	0.975	1.000	.002	46	view →
COAD	OS	Tertile	II,III,IV	0.824	0.517	.007	29	view →
UVM	DFS	Quartile	III,IV	0.345	0.758	.002	24	view →
PRAD	DFS	Tertile	All	0.709	0.877	<.001	24	view →
OV	DFS	Tertile	II,III,IV	0.352	0.442	.026	20	view →
LGG	DFS	Quartile	All	0.739	0.889	.005	17	view →
LIHC	OS	Quartile	III,IV	0.477	0.771	.004	15	view →
SKCM	OS	Median	II,III,IV	0.637	0.795	.008	14	view →
KICH	DFS	Quartile	III,IV	0.197	0.738	.007	8	view →
PAAD	OS	Tertile	All	0.495	0.246	.027	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

DNAJB5-DT–LUAD (DFS)

Open the LUAD breakdown →