DNAJB4

Across TCGA pan-cancer cohorts, DNAJB4 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DNAJB4 data layer compared with 27 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DNAJB4 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DNAJB4 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

LUAD, PDAC, and HNSC are the cancer types where DNAJB4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	III,IV	0.256	0.812	.014	12	view →
PDAC	DFS	Tertile	All	0.476	0.268	.026	8	view →
HNSC	DFS	Tertile	All	0.694	0.877	.028	2	view →
LSCC	DFS	Quartile	III,IV	0.504	1.000	.042	1	view →
GBM	OS	Tertile	All	0.900	0.721	.028	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DNAJB4–LUAD (OS)

Open the LUAD breakdown →