Across TCGA patient cohorts, DNAJB13 mutation is significantly associated with the RNA expression of many other genes, with 1,036 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJB13-associated genes across cancer lineages are CDK11B, COX15, and TEDC2. Each is linked with DNAJB13 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJB13-to-partner and partner-to-DNAJB13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB13→partner) and Y-score (partner→DNAJB13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CDK11B →	+0.492	+3.227	.002	.009	3	2
UCEC	COX15 →	+0.434	+3.329	.005	.005	3	2
UCEC	TEDC2 →	+0.673	+2.928	.001	.001	3	2
UCEC	CDC25A →	+0.718	+2.609	.002	.006	3	2
UCEC	PTTG1 →	+0.691	+2.906	.009	.002	3	2
UCEC	HSPA4 →	+0.531	+3.191	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,036 associations by consensus.

Exploration

DNAJB13 survival (RNA) · tumor vs normal (RNA) · all DNAJB13 data types