Across TCGA patient cohorts, DNAJB13 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJB13-associated genes across cancer lineages are p38-MAPK_pT180_Y182, EGFR_pY1068, and A-Raf_pS299. Each is linked with DNAJB13 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJB13-to-partner and partner-to-DNAJB13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB13→partner) and Y-score (partner→DNAJB13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p38-MAPK_pT180_Y182 →	-0.408	-2.321	.044	.034	3	2
UCEC	EGFR_pY1068 →	-0.284	-2.700	.012	.006	3	1
UCEC	A-Raf_pS299 →	-0.184	-3.459	<.001	.005	2	2
UCEC	FASN →	+0.434	+2.000	.014	.032	3	1
UCEC	FoxM1 →	+0.245	+2.000	.036	.032	3	1
UCEC	JNK_pT183_Y185 →	-0.215	-1.986	.004	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

DNAJB13 survival (RNA) · tumor vs normal (RNA) · all DNAJB13 data types