DNAJB13

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DNAJB13 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJB13-associated genes across cancer lineages are DPP6, ASZ1, and TRIM49B. Each is linked with DNAJB13 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJB13-to-partner and partner-to-DNAJB13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB13→partner) and Y-score (partner→DNAJB13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaDPP6 →+0.293+3.623.004.00731
BLOOD_LeukemiaASZ1 →+0.104+3.567<.001.00331
BLOOD_LeukemiaTRIM49B →+0.092+3.289<.001.00931
BLOOD_LeukemiaACTN3 →+0.064+3.504.008.00931
BLOOD_LeukemiaCFHR2 →+0.204+4.539<.001<.00131
BLOOD_LeukemiaIL13RA2 →+0.313+3.509<.001.00821
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration