DNAJB12

Across TCGA cell cohorts, DNAJB12 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAJB12-associated genes across cancer lineages are FAM236A, HSFY1, and AMELY. Each is linked with DNAJB12 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJB12-to-partner and partner-to-DNAJB12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM236A grouped by DNAJB12-low versus DNAJB12-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB12→partner) and Y-score (partner→DNAJB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	FAM236A →	+0.120	+5.357	<.001	.003	3	1
LARGE_INTESTINE	HSFY1 →	+0.019	+4.415	<.001	.007	3	1
LARGE_INTESTINE	AMELY →	+0.045	+5.022	<.001	.002	3	1
BLOOD_Leukemia	TLE7 →	+0.032	+4.969	<.001	.003	3	1
BLOOD_Leukemia	POTEI →	+0.178	+4.392	<.001	.005	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

FAM236A by DNAJB12 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →