DNAJB11

Across TCGA patient cohorts, DNAJB11 mutation is significantly associated with the RNA expression of many other genes, with 413 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJB11-associated genes across cancer lineages are H3Y1, RN7SKP181, and RPL7P35. Each is linked with DNAJB11 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJB11-to-partner and partner-to-DNAJB11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H3Y1 grouped by DNAJB11-low versus DNAJB11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB11→partner) and Y-score (partner→DNAJB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	H3Y1 →	+1.249	+1.678	<.001	.005	3	2
UCEC	RN7SKP181 →	+0.097	+2.368	<.001	.004	3	2
UCEC	RPL7P35 →	+0.066	+2.356	.004	<.001	3	2
UCEC	RNA5SP410 →	+0.488	+1.981	.001	.003	3	2
UCEC	RNA5SP415 →	+0.460	+2.389	<.001	.001	3	2
UCEC	MIR8082 →	+0.423	+2.462	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 413 associations by consensus.

H3Y1 by DNAJB11 expression — UCEC

Explore this box plot interactively →