DNAJB1

Across TCGA pan-cancer cohorts, DNAJB1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DNAJB1 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DNAJB1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DNAJB1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, LSCC, and CCRCC are the cancer types where DNAJB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	III,IV	1.000	0.895	.039	12	view →
LSCC	DFS	Median	II,III,IV	1.000	0.841	.007	7	view →
CCRCC	DFS	Tertile	All	0.970	0.481	.010	5	view →
UCEC	DFS	Median	II,III,IV	0.882	0.533	.035	4	view →
HNSC	DFS	Tertile	IV	0.573	0.790	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DNAJB1–COAD (DFS)

Open the COAD breakdown →