DNAJB1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DNAJB1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,508 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNAJB1-associated genes across cancer lineages are GIPC1, ZNF823, and STX10. Each is linked with DNAJB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DNAJB1-to-partner and partner-to-DNAJB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAJB1 versus GIPC1 in HNSC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB1→partner) and Y-score (partner→DNAJB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCGIPC1 →+1.051+0.476<.001<.00137
LSCCZNF823 →+0.654+0.531<.001<.00137
UCECSTX10 →+0.725+0.222.006.00336
OVC19orf53 →+0.785+0.592<.001<.00136
HNSCRPL18A →+0.951+0.324.002<.00136
LSCCSYNE3 →-0.668-0.422<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,508 associations by consensus.

DNAJB1 vs GIPC1 — HNSC

Per-sample scatter of DNAJB1 vs GIPC1 in HNSC (Pearson r = 0.53).

Explore this scatter interactively →

Exploration