DNAJA4

Across TCGA pan-cancer cohorts, DNAJA4 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DNAJA4 data layer compared with 28 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DNAJA4 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DNAJA4 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC, CCRCC, and LUAD are the cancer types where DNAJA4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.968	0.813	.007	12	view →
CCRCC	DFS	Median	All	0.839	0.653	.011	11	view →
LUAD	OS	Tertile	All	0.569	0.987	.005	10	view →
PDAC	OS	Quartile	All	0.630	0.347	.013	2	view →
LSCC	OS	Median	All	1.000	0.800	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DNAJA4–UCEC (DFS)

Open the UCEC breakdown →