DNAJA2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DNAJA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,486 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJA2-associated GO terms across cancer lineages are Regulation of locomotion involved in locomotory behavior, Negative regulation of nuclear-transcribed mRNA poly(A) tail shortening, and Positive regulation of dopamine receptor signaling pathway. Each is linked with DNAJA2 in more than 11 cancer types. Because this analysis shows association rather than direction, both DNAJA2-to-partner and partner-to-DNAJA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of locomotion involved in locomotory behavior grouped by DNAJA2-low versus DNAJA2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJA2→partner) and Y-score (partner→DNAJA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCRegulation of locomotion involved in locomotory behavior →+0.316+0.477<.001.001312
LIVERNegative regulation of nuclear-transcribed mRNA poly(A) tail shortening →+0.117+0.674.001.002311
URINARY_TRACTPositive regulation of dopamine receptor signaling pathway →+0.188+0.541.002.004311
BONEPositive regulation of amine metabolic process →+0.194+0.707.003.00139
UPPER_AERODIGESTIVE_TRACTSymbiont-mediated disruption of host cell PML body →+0.083+0.547.001.00639
BLOOD_LeukemiasnRNA processing →+0.039+0.386.005<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,486 associations by consensus.

Regulation of locomotion involved in locomotory behavior by DNAJA2 expression — LUNG_SCLC

Box plot of Regulation of locomotion involved in locomotory behavior in DNAJA2-low vs DNAJA2-high samples in LUNG_SCLC.

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Exploration