DNAJA1

Across TCGA pan-cancer cohorts, DNAJA1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DNAJA1 data layer compared with 20 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DNAJA1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DNAJA1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, PDAC, and COAD are the cancer types where DNAJA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.977	0.504	.005	28	view →
PDAC	OS	Median	III,IV	0.510	0.968	.005	26	view →
COAD	DFS	Median	IV	0.565	1.000	.028	6	view →
HNSC	OS	Quartile	IV	0.994	0.649	.013	4	view →
GBM	OS	Tertile	All	0.910	0.775	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DNAJA1–LUAD (DFS)

Open the LUAD breakdown →