DNAI3

Across TCGA patient cohorts, DNAI3 protein abundance is significantly associated with the RNA expression of many other genes, with 418 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNAI3-associated genes across cancer lineages are RNU6-9, GPR45, and GTF2B. Each is linked with DNAI3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAI3-to-partner and partner-to-DNAI3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAI3 versus RNU6-9 in LUAD, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAI3→partner) and Y-score (partner→DNAI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-9 →	+1.142	+1.120	<.001	.003	3	2
LUAD	GPR45 →	-0.221	-0.969	.001	.001	3	1
LUAD	GTF2B →	+0.509	+0.969	.003	.001	3	1
LUAD	NLRP4 →	+0.131	+0.996	<.001	.001	3	1
LUAD	FUBP1 →	+0.512	+1.011	.001	<.001	3	1
LUAD	C1orf52 →	+0.474	+0.948	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 418 associations by consensus.

DNAI3 vs RNU6-9 — LUAD

Explore this scatter interactively →