DNAI2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DNAI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,141 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DNAI2-associated GO terms across cancer lineages are Regulation of proteasomal protein catabolic process, Regulation of macroautophagy, and Antigen processing and presentation of exogenous antigen. Each is linked with DNAI2 in more than 4 cancer types. Because this analysis shows association rather than direction, both DNAI2-to-partner and partner-to-DNAI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of proteasomal protein catabolic process grouped by DNAI2-low versus DNAI2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAI2→partner) and Y-score (partner→DNAI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaRegulation of proteasomal protein catabolic process →+0.035+0.123.001.00635
BLOOD_LymphomaRegulation of macroautophagy →+0.033+0.120.001.00934
BLOOD_LymphomaAntigen processing and presentation of exogenous antigen →+0.112+0.108<.001.00134
BLOOD_LymphomaResponse to lipopolysaccharide →+0.033+0.126.001.00734
BLOOD_LymphomaCellular response to oxidative stress →+0.024+0.109.001.00134
BLOOD_LymphomaRegulation of lymphocyte differentiation →+0.050+0.176<.001.00434
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,141 associations by consensus.

Regulation of proteasomal protein catabolic process by DNAI2 expression — BLOOD_Lymphoma

Box plot of Regulation of proteasomal protein catabolic process in DNAI2-low vs DNAI2-high samples in BLOOD_Lymphoma.

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