DNAH9

Across TCGA patient cohorts, DNAH9 mutation is significantly associated with the RNA expression of many other genes, with 11,030 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAH9-associated genes across cancer lineages are SPAG5, KIF20A, and NCAPG. Each is linked with DNAH9 in more than 7 cancer types. Because this analysis shows association rather than direction, both DNAH9-to-partner and partner-to-DNAH9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPAG5 grouped by DNAH9-low versus DNAH9-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH9→partner) and Y-score (partner→DNAH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SPAG5 →	+0.446	+0.943	.001	.003	3	8
CESC	KIF20A →	+0.572	+2.629	.004	.004	3	7
STAD	NCAPG →	+0.635	+2.688	<.001	<.001	3	7
UCEC	NUSAP1 →	+0.531	+1.230	<.001	<.001	3	7
COAD	PBK →	+0.904	+2.232	<.001	<.001	3	7
STAD	ACKR1 →	-0.909	-1.822	.006	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,030 associations by consensus.

SPAG5 by DNAH9 expression — LUAD

Explore this box plot interactively →