DNAH9

Across TCGA patient cohorts, DNAH9 mutation is significantly associated with the total protein of many other genes, with 116 significant associations in total. COAD shows the largest number of these associations.

The most reproducible DNAH9-associated genes across cancer lineages are Cyclin-B1, Caspase-7-cleavedD198, and ASNS. Each is linked with DNAH9 in more than 6 cancer types. Because this analysis shows association rather than direction, both DNAH9-to-partner and partner-to-DNAH9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by DNAH9-low versus DNAH9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH9→partner) and Y-score (partner→DNAH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.398	+1.115	.001	<.001	3	7
COAD	Caspase-7-cleavedD198 →	+1.224	+2.601	<.001	<.001	3	6
COAD	ASNS →	+0.548	+1.901	<.001	<.001	3	6
STAD	MYH11 →	-1.146	-2.115	.010	.016	3	5
STAD	Caveolin-1 →	-0.684	-2.906	.002	.001	3	5
COAD	c-Kit →	-0.511	-1.406	.002	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 116 associations by consensus.

Cyclin-B1 by DNAH9 expression — UCEC

Explore this box plot interactively →