DNAH9

Across TCGA cell cohorts, DNAH9 mutation is significantly associated with the RNA expression of many other genes, with 1,807 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAH9-associated genes across cancer lineages are HSFX4, OR51Q1, and B9D1. Each is linked with DNAH9 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNAH9-to-partner and partner-to-DNAH9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSFX4 grouped by DNAH9-low versus DNAH9-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH9→partner) and Y-score (partner→DNAH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	HSFX4 →	+0.076	+2.977	<.001	.003	3	3
LUNG_SCLC	OR51Q1 →	+0.090	+2.288	<.001	<.001	3	3
URINARY_TRACT	B9D1 →	+1.107	+3.160	.004	.006	3	3
LUNG_NSCLC_LUAD	MDH1B →	+0.330	+1.914	.006	.003	3	3
SKIN	BACH2 →	-0.331	-1.517	.002	.005	3	3
LARGE_INTESTINE	C6orf52 →	+0.636	+2.000	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,807 associations by consensus.

HSFX4 by DNAH9 expression — OESOPHAGUS

Explore this box plot interactively →