DNAH8

Across TCGA cell cohorts, DNAH8 RNA expression is significantly associated with the go_rna of many other GO terms, with 879 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAH8-associated GO terms across cancer lineages are Natural killer cell tolerance induction, Aminoacyl-tRNA metabolism involved in translational fidelity, and Outflow tract septum morphogenesis. Each is linked with DNAH8 in more than 4 cancer types. Because this analysis shows association rather than direction, both DNAH8-to-partner and partner-to-DNAH8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Natural killer cell tolerance induction grouped by DNAH8-low versus DNAH8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH8→partner) and Y-score (partner→DNAH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Natural killer cell tolerance induction →	-0.218	-0.010	.001	.009	2	5
BLOOD_Leukemia	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.062	+0.392	<.001	.003	3	3
BREAST	Outflow tract septum morphogenesis →	-0.106	-0.087	<.001	.006	3	3
BLOOD_Leukemia	Adaptive thermogenesis →	+0.058	+0.449	<.001	.001	3	3
BLOOD_Leukemia	snRNA pseudouridine synthesis →	+0.033	+0.334	<.001	.003	3	3
BLOOD_Leukemia	Tetrapyrrole biosynthetic process →	+0.081	+0.330	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 879 associations by consensus.

Natural killer cell tolerance induction by DNAH8 expression — BONE

Explore this box plot interactively →