DNAH8-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DNAH8-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated DNAH8-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher DNAH8-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated DNAH8-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and LUAD show a favorable association.

BLCA, ACC, and KICH are the cancer types where DNAH8-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCADFSMedianIII,IV0.5990.374<.001125view →
ACCDFSTertileIII,IV0.0100.364<.001108view →
KICHDFSTertileAll0.4290.914<.00187view →
KIRCOSTertileAll0.5550.730<.00170view →
LUADOSQuartileAll0.7910.607<.00158view →
ESCADFSTertileIII,IV0.5490.240.00442view →
BRCAOSMedianIII,IV0.7220.444.00140view →
OVOSTertileIII,IV0.3860.284.02038view →
CHOLDFSTertileAll1.0000.266.01527view →
LUSCDFSQuartileIII,IV0.5800.241.00716view →
SKCMDFSMedianIV0.7630.187.00611view →
PAADOSTertileII,III,IV0.6870.512.01710view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

DNAH8-AS1–BLCA (DFS)

Kaplan–Meier survival curve for DNAH8-AS1 RNA-high vs -low samples in BLCA.

Open the BLCA breakdown →

Exploration