DNAH7

Across TCGA patient cohorts, DNAH7 protein abundance is significantly associated with the RNA expression of many other genes, with 3,000 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DNAH7-associated genes across cancer lineages are SPHKAP, LGI4, and AGBL2. Each is linked with DNAH7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAH7-to-partner and partner-to-DNAH7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAH7 versus SPHKAP in LUAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH7→partner) and Y-score (partner→DNAH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SPHKAP →	+0.158	+0.917	.002	<.001	3	2
LSCC	LGI4 →	+0.536	+1.265	<.001	<.001	3	2
LSCC	AGBL2 →	+0.819	+1.205	<.001	<.001	3	2
LUAD	RSPH14 →	+0.727	+1.047	<.001	<.001	3	1
LUAD	CCDC198 →	+1.149	+0.739	.001	.002	3	1
LUAD	SLC8A3 →	+0.388	+0.731	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,000 associations by consensus.

DNAH7 vs SPHKAP — LUAD

Explore this scatter interactively →