DNAH5

Across TCGA cell cohorts, DNAH5 mutation is significantly associated with the RNA expression of many other genes, with 1,053 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAH5-associated genes across cancer lineages are FOXD2, GADL1, and RPL17. Each is linked with DNAH5 in more than 3 cancer types. Because this analysis shows association rather than direction, both DNAH5-to-partner and partner-to-DNAH5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXD2 grouped by DNAH5-low versus DNAH5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH5→partner) and Y-score (partner→DNAH5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FOXD2 →	+0.450	+2.574	<.001	.003	3	4
URINARY_TRACT	GADL1 →	+0.012	+3.050	<.001	.007	3	3
PANCREAS	RPL17 →	+0.790	+3.378	<.001	.002	3	3
SKIN	CEP76 →	+0.308	+0.906	.005	.007	3	3
BLOOD_Leukemia	CPNE7 →	+1.323	+1.614	.009	.004	3	3
BLOOD_Leukemia	NSD2 →	+0.620	+1.614	.003	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,053 associations by consensus.

FOXD2 by DNAH5 expression — BLOOD_Leukemia

Explore this box plot interactively →