Across TCGA patient cohorts, DNAH2 mutation is significantly associated with the total protein of many other genes, with 115 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAH2-associated genes across cancer lineages are Caspase-7-cleavedD198, ASNS, and Cyclin-B1. Each is linked with DNAH2 in more than 4 cancer types. Because this analysis shows association rather than direction, both DNAH2-to-partner and partner-to-DNAH2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH2→partner) and Y-score (partner→DNAH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.163	+1.708	<.001	.001	3	5
COAD	ASNS →	+0.373	+1.502	<.001	.023	3	5
LUAD	Cyclin-B1 →	+0.713	+3.321	<.001	.009	3	4
UCEC	Chk2_pT68 →	-0.138	-1.880	<.001	<.001	3	4
COAD	MIG-6 →	+0.060	+1.597	.029	.004	3	4
UCEC	eEF2 →	+0.219	+1.637	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 115 associations by consensus.

Exploration

DNAH2 survival (RNA) · tumor vs normal (RNA) · all DNAH2 data types