Across TCGA patient cohorts, DNAH17 mutation is significantly associated with the RNA expression of many other genes, with 9,357 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAH17-associated genes across cancer lineages are DLGAP5, PARP2, and COQ3. Each is linked with DNAH17 in more than 6 cancer types. Because this analysis shows association rather than direction, both DNAH17-to-partner and partner-to-DNAH17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH17→partner) and Y-score (partner→DNAH17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DLGAP5 →	+1.160	+2.819	<.001	<.001	3	7
LUAD	PARP2 →	+0.555	+2.321	<.001	.001	3	7
LUAD	COQ3 →	+0.541	+2.127	<.001	.009	3	7
LUAD	CDCA8 →	+1.279	+2.819	<.001	<.001	3	7
LUAD	NUSAP1 →	+1.003	+2.918	<.001	<.001	3	7
LUAD	KIF2C →	+1.355	+3.169	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,357 associations by consensus.

Exploration

DNAH17 survival (RNA) · tumor vs normal (RNA) · all DNAH17 data types