Across TCGA patient cohorts, DNAH17 mutation is significantly associated with the total protein of many other genes, with 113 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAH17-associated genes across cancer lineages are c-Kit, ASNS, and PCNA. Each is linked with DNAH17 in more than 5 cancer types. Because this analysis shows association rather than direction, both DNAH17-to-partner and partner-to-DNAH17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH17→partner) and Y-score (partner→DNAH17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	c-Kit →	-0.301	-0.807	.036	.009	3	6
LUAD	ASNS →	+0.660	+3.584	<.001	.002	3	5
LUAD	PCNA →	+0.282	+3.584	<.001	.002	3	5
COAD	GAPDH →	+0.411	+1.696	.002	<.001	3	5
READ	FASN →	+0.585	+3.169	.007	.016	3	4
LUAD	YAP_pS127 →	-0.383	-3.459	.005	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 113 associations by consensus.

Exploration

DNAH17 survival (RNA) · tumor vs normal (RNA) · all DNAH17 data types