Across TCGA cell cohorts, DNAH17 mutation is significantly associated with the RNA expression of many other genes, with 1,451 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAH17-associated genes across cancer lineages are PTCH2, LRRD1, and CTSZ. Each is linked with DNAH17 in more than 4 cancer types. Because this analysis shows association rather than direction, both DNAH17-to-partner and partner-to-DNAH17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH17→partner) and Y-score (partner→DNAH17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PTCH2 →	+0.649	+3.459	<.001	.003	3	5
URINARY_TRACT	LRRD1 →	+0.041	+2.237	.001	.003	3	4
BLOOD_Leukemia	CTSZ →	-1.642	-1.555	.005	.008	3	4
LARGE_INTESTINE	HAUS1 →	+0.478	+1.351	.009	.001	3	4
OVARY	OR2AG1 →	+0.028	+3.247	.001	.005	3	4
STOMACH	C16orf96 →	+0.096	+2.662	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,451 associations by consensus.

Exploration

DNAH17 survival (RNA) · tumor vs normal (RNA) · all DNAH17 data types