Across TCGA patient cohorts, DNAH14 mutation is significantly associated with the total protein of many other genes, with 73 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAH14-associated genes across cancer lineages are C-Raf, GAPDH, and INPP4B. Each is linked with DNAH14 in more than 3 cancer types. Because this analysis shows association rather than direction, both DNAH14-to-partner and partner-to-DNAH14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH14→partner) and Y-score (partner→DNAH14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C-Raf →	+0.227	+3.008	<.001	<.001	3	4
BRCA	GAPDH →	+1.334	+3.000	<.001	.038	3	3
COAD	INPP4B →	-0.305	-1.874	.027	.047	3	3
COAD	Caspase-7-cleavedD198 →	+1.071	+3.584	<.001	.002	2	4
UCEC	Notch1 →	+0.084	+1.138	.015	.016	3	3
UCEC	Cyclin-B1 →	+0.321	+1.247	.020	.038	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

Exploration

DNAH14 survival (RNA) · tumor vs normal (RNA) · all DNAH14 data types