DNAH12

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DNAH12 protein abundance is significantly associated with the RNA expression of many other genes, with 750 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNAH12-associated genes across cancer lineages are GOLPH3, RAD1, and CCDC3. Each is linked with DNAH12 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAH12-to-partner and partner-to-DNAH12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAH12 versus GOLPH3 in LUAD, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH12→partner) and Y-score (partner→DNAH12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADGOLPH3 →-0.412-0.781.004.00131
LUADRAD1 →-0.530-0.638.003.00531
LUADCCDC3 →+0.464+0.658.004.00931
LUADFBXO4 →-0.670-0.932<.001<.00131
LUADBMERB1 →+0.558+0.621.003.00731
LUADDNAJC21 →-0.495-0.701.003.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 750 associations by consensus.

DNAH12 vs GOLPH3 — LUAD

Per-sample scatter of DNAH12 vs GOLPH3 in LUAD (Pearson r = -0.50).

Explore this scatter interactively →

Exploration