DNAH12

Across TCGA cell cohorts, DNAH12 mutation is significantly associated with the RNA expression of many other genes, with 336 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAH12-associated genes across cancer lineages are CHIA, ARHGAP44, and LCE1D. Each is linked with DNAH12 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNAH12-to-partner and partner-to-DNAH12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHIA grouped by DNAH12-low versus DNAH12-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH12→partner) and Y-score (partner→DNAH12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CHIA →	+1.107	+4.087	.002	.009	3	3
SKIN	ARHGAP44 →	+0.425	+2.506	<.001	.006	3	3
OESOPHAGUS	LCE1D →	+0.206	+4.906	<.001	.006	3	2
STOMACH	OR52H1 →	+0.078	+3.794	.001	.003	3	2
BLOOD_Lymphoma	FASLG →	+2.817	+3.091	<.001	.003	3	2
BLOOD_Lymphoma	CRP →	+0.145	+2.938	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 336 associations by consensus.

CHIA by DNAH12 expression — URINARY_TRACT

Explore this box plot interactively →