DNAH10OS

Across TCGA pan-cancer cohorts, DNAH10OS RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated DNAH10OS data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher DNAH10OS RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DNAH10OS expression acts as an unfavorable survival marker, although some lineages such as UCS and PAAD show a favorable association.

LUSC, UVM, and UCS are the cancer types where DNAH10OS RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	III,IV	0.386	0.685	<.001	75	view →
UVM	DFS	Median	All	0.429	0.718	.001	46	view →
UCS	OS	Tertile	III,IV	0.672	0.267	.016	46	view →
CESC	DFS	Tertile	All	0.758	0.898	<.001	46	view →
PAAD	DFS	Quartile	All	0.582	0.326	<.001	38	view →
BLCA	DFS	Median	All	0.690	0.559	.004	31	view →
HNSC	DFS	Tertile	III,IV	0.401	0.277	.009	21	view →
CHOL	DFS	Median	All	0.727	0.227	.012	18	view →
SKCM	OS	Median	IV	0.779	0.196	<.001	18	view →
ACC	DFS	Median	All	0.534	0.781	.004	13	view →
LIHC	DFS	Quartile	All	0.428	0.563	.011	13	view →
PCPG	OS	Median	All	0.934	1.000	.015	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

DNAH10OS–LUSC (DFS)

Open the LUSC breakdown →