Across TCGA patient cohorts, DNAH10 mutation is significantly associated with the total protein of many other genes, with 109 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAH10-associated genes across cancer lineages are Cyclin-E2, PCNA, and Caspase-7-cleavedD198. Each is linked with DNAH10 in more than 5 cancer types. Because this analysis shows association rather than direction, both DNAH10-to-partner and partner-to-DNAH10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH10→partner) and Y-score (partner→DNAH10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Cyclin-E2 →	+0.195	+2.584	.003	<.001	3	6
COAD	PCNA →	+0.222	+1.146	.001	.026	3	6
COAD	Caspase-7-cleavedD198 →	+1.108	+2.441	<.001	<.001	3	6
UCEC	Cyclin-B1 →	+0.442	+1.632	<.001	<.001	3	6
LUSC	MYH11 →	-0.751	-2.321	.021	.031	3	5
UCEC	4E-BP1 →	+0.197	+1.584	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 109 associations by consensus.

Exploration

DNAH10 survival (RNA) · tumor vs normal (RNA) · all DNAH10 data types