Across TCGA cell cohorts, DNAH10 mutation is significantly associated with the RNA expression of many other genes, with 1,955 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAH10-associated genes across cancer lineages are TEX46, BBS7, and CFAP157. Each is linked with DNAH10 in more than 3 cancer types. Because this analysis shows association rather than direction, both DNAH10-to-partner and partner-to-DNAH10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH10→partner) and Y-score (partner→DNAH10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TEX46 →	+0.143	+3.736	.002	.004	3	4
LARGE_INTESTINE	BBS7 →	+0.588	+2.700	<.001	<.001	3	4
LARGE_INTESTINE	CFAP157 →	+0.364	+1.386	.004	.007	3	3
LARGE_INTESTINE	INTS2 →	+0.645	+1.706	<.001	<.001	3	3
LARGE_INTESTINE	FTSJ3 →	+0.495	+1.405	.001	.005	3	3
LARGE_INTESTINE	NKTR →	+0.640	+1.807	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,955 associations by consensus.

Exploration

DNAH10 survival (RNA) · tumor vs normal (RNA) · all DNAH10 data types