DNAAF6

Across TCGA cell cohorts, DNAAF6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,283 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAAF6-associated GO terms across cancer lineages are T cell differentiation in thymus, Regulation of humoral immune response, and Negative regulation of chaperone-mediated autophagy. Each is linked with DNAAF6 in more than 5 cancer types. Because this analysis shows association rather than direction, both DNAAF6-to-partner and partner-to-DNAAF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T cell differentiation in thymus grouped by DNAAF6-low versus DNAAF6-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAAF6→partner) and Y-score (partner→DNAAF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	T cell differentiation in thymus →	+0.104	+0.014	<.001	.004	3	6
BREAST	Regulation of humoral immune response →	+0.137	+0.025	.004	.003	3	5
LUNG_SCLC	Negative regulation of chaperone-mediated autophagy →	-0.141	-0.093	.009	.005	3	5
UPPER_AERODIGESTIVE_TRACT	L-amino acid transport →	-0.055	-0.013	.005	.009	3	4
STOMACH	Spermatid development →	-0.038	-0.022	.002	.007	3	4
SKIN	Regulation of lung ciliated cell differentiation →	+1.824	+0.016	<.001	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,283 associations by consensus.

T cell differentiation in thymus by DNAAF6 expression — SOFT_TISSUE

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