DNAAF5

Across TCGA cell cohorts, DNAAF5 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAAF5-associated genes across cancer lineages are LY6G6F, EXOC1L, and HOXD12. Each is linked with DNAAF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAAF5-to-partner and partner-to-DNAAF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LY6G6F grouped by DNAAF5-low versus DNAAF5-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAAF5→partner) and Y-score (partner→DNAAF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LY6G6F →	+0.029	+4.093	<.001	.004	3	2
OESOPHAGUS	EXOC1L →	+0.036	+4.906	<.001	.006	3	1
BREAST	HOXD12 →	+0.117	+3.468	<.001	.007	3	1
BREAST	DNAI2 →	+0.026	+3.554	<.001	.001	3	1
BREAST	C10orf99 →	+0.612	+2.906	<.001	.007	3	1
BREAST	MT1H →	+0.114	+2.830	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

LY6G6F by DNAAF5 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →