DNAAF2

Across TCGA patient cohorts, DNAAF2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,064 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNAAF2-associated genes across cancer lineages are MARCHF10, PAQR4, and LRR1. Each is linked with DNAAF2 in more than 4 cancer types. Because this analysis shows association rather than direction, both DNAAF2-to-partner and partner-to-DNAAF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAAF2 versus MARCHF10 in UCEC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAAF2→partner) and Y-score (partner→DNAAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MARCHF10 →	+0.837	+0.412	<.001	<.001	3	5
OV	PAQR4 →	+0.772	+0.340	.005	.003	3	4
LSCC	LRR1 →	+0.723	+0.380	<.001	<.001	3	4
UCEC	LRWD1 →	+0.819	+0.504	.002	<.001	3	4
BRCA	POLE2 →	+0.589	+0.328	<.001	<.001	3	3
LSCC	DLGAP5 →	+1.037	+0.362	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,064 associations by consensus.

DNAAF2 vs MARCHF10 — UCEC

Explore this scatter interactively →