DNAAF2

Across TCGA patient cohorts, DNAAF2 mutation is significantly associated with the RNA expression of many other genes, with 3,182 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAAF2-associated genes across cancer lineages are RNA5SP321, MIR7702, and LRRC8A. Each is linked with DNAAF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAAF2-to-partner and partner-to-DNAAF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP321 grouped by DNAAF2-low versus DNAAF2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAAF2→partner) and Y-score (partner→DNAAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP321 →	+0.184	+4.289	.002	.007	3	2
UCEC	MIR7702 →	+0.229	+4.253	<.001	.004	3	2
UCEC	LRRC8A →	+0.536	+3.608	.006	.001	3	2
UCEC	YWHAZP5 →	+0.723	+2.818	.004	.001	3	2
UCEC	SETP22 →	+0.336	+4.015	<.001	<.001	3	2
UCEC	KCNIP2-AS1 →	+0.417	+3.467	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,182 associations by consensus.

RNA5SP321 by DNAAF2 expression — BLCA

Explore this box plot interactively →