DNAAF2

Across TCGA cell cohorts, DNAAF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,131 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DNAAF2-associated GO terms across cancer lineages are Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), tRNA metabolic process, and tRNA modification. Each is linked with DNAAF2 in more than 13 cancer types. Because this analysis shows association rather than direction, both DNAAF2-to-partner and partner-to-DNAAF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by DNAAF2-low versus DNAAF2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAAF2→partner) and Y-score (partner→DNAAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.094	+0.651	<.001	<.001	3	14
BLOOD_Lymphoma	tRNA metabolic process →	+0.054	+0.872	<.001	<.001	3	13
LUNG_NSCLC_LUSC	tRNA modification →	+0.071	+0.951	.002	.003	3	13
SKIN	tRNA processing →	+0.042	+0.594	<.001	<.001	3	13
BREAST	tRNA methylation →	+0.068	+0.750	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitochondrial tRNA methylation →	+0.145	+0.836	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,131 associations by consensus.

Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by DNAAF2 expression — OVARY

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