DNAAF1

Across TCGA pan-cancer cohorts, DNAAF1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DNAAF1 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DNAAF1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DNAAF1 expression acts as an unfavorable survival marker.

LUAD, GBM, and UCEC are the cancer types where DNAAF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.352	0.802	<.001	26	view →
GBM	OS	Tertile	All	0.256	0.574	.003	10	view →
UCEC	OS	Quartile	All	0.891	1.000	.048	2	view →
LSCC	DFS	Median	II,III,IV	0.863	0.969	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DNAAF1–LUAD (DFS)

Open the LUAD breakdown →