DNAAF1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DNAAF1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,941 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DNAAF1-associated genes across cancer lineages are RBM28, CCSAP, and PAXIP1. Each is linked with DNAAF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNAAF1-to-partner and partner-to-DNAAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAAF1 versus RBM28 in GBM, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAAF1→partner) and Y-score (partner→DNAAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRBM28 →-0.361-0.783<.001<.00133
UCECCCSAP →-0.478-0.667.002.00433
GBMPAXIP1 →-0.356-0.723<.001<.00133
LSCCFLVCR1 →-0.560-0.781<.001.00333
GBMZNF507 →-0.397-0.679<.001.00233
LSCCFBXO45 →-0.795-0.982<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,941 associations by consensus.

DNAAF1 vs RBM28 — GBM

Per-sample scatter of DNAAF1 vs RBM28 in GBM (Pearson r = -0.48).

Explore this scatter interactively →

Exploration