Across TCGA patient cohorts, DMWD RNA expression is significantly associated with the protein abundance of many other proteins, with 13,940 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DMWD-associated proteins across cancer lineages are DENND2D, PPP5C, and PSME2. Each is linked with DMWD in more than 5 cancer types. Because this analysis shows association rather than direction, both DMWD-to-partner and partner-to-DMWD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMWD→partner) and Y-score (partner→DMWD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DENND2D →	-0.712	-0.434	.004	.008	3	6
OV	PPP5C →	+0.312	+0.720	.005	.004	3	5
OV	PSME2 →	-0.412	-0.816	.006	.001	3	5
GBM	TRIM28 →	+0.369	+0.383	<.001	<.001	3	5
GBM	PAFAH1B3 →	+0.353	+0.487	<.001	<.001	3	5
GBM	SAE1 →	+0.346	+0.391	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,940 associations by consensus.

Exploration

DMWD survival (RNA) · tumor vs normal (RNA) · all DMWD data types