DMTN

Across TCGA pan-cancer cohorts, DMTN Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DMTN data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher DMTN Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DMTN expression acts as an unfavorable survival marker.

UCS, KICH, and PRAD are the cancer types where DMTN Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	All	0.135	0.687	.009	24	view →
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
LUSC	OS	Median	All	0.138	0.818	.003	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
THCA	OS	Median	All	0.342	0.955	<.001	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DMTN–UCS (OS)

Open the UCS breakdown →