DMTN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DMTN RNA expression is significantly associated with the protein abundance of many other proteins, with 13,894 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DMTN-associated proteins across cancer lineages are DMTN_S16, DMTN_S156, and DMTN_S26. Each is linked with DMTN in more than 8 cancer types. Because this analysis shows association rather than direction, both DMTN-to-partner and partner-to-DMTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMTN versus DMTN_S16 in OV, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMTN→partner) and Y-score (partner→DMTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVDMTN_S16 →+1.318+1.480<.001<.00139
PDACDMTN_S156 →+0.777+0.742<.001<.00138
HNSCDMTN_S26 →+0.637+0.786<.001.00638
LSCCGSR →+0.471+0.592<.001<.00138
CCRCCMYO9B →-0.238-0.976.005<.00136
GBMSPTAN1 →+0.277+0.810<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,894 associations by consensus.

DMTN vs DMTN_S16 — OV

Per-sample scatter of DMTN vs DMTN_S16 in OV (Pearson r = 0.50).

Explore this scatter interactively →

Exploration