DMTN

Across TCGA patient cohorts, DMTN protein abundance is significantly associated with the RNA expression of many other genes, with 4,979 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DMTN-associated genes across cancer lineages are HBA2, HBB, and HBA1. Each is linked with DMTN in more than 7 cancer types. Because this analysis shows association rather than direction, both DMTN-to-partner and partner-to-DMTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMTN versus HBA2 in LUAD, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMTN→partner) and Y-score (partner→DMTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HBA2 →	+1.878	+0.532	<.001	<.001	3	8
BRCA	HBB →	+2.249	+0.900	<.001	<.001	3	8
LUAD	HBA1 →	+1.329	+0.485	<.001	<.001	3	7
CCRCC	HEMGN →	+0.523	+0.521	<.001	<.001	3	6
GBM	PF4 →	+0.876	+0.585	<.001	<.001	3	5
LUAD	FOSB →	+1.307	+0.289	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,979 associations by consensus.

DMTN vs HBA2 — LUAD

Explore this scatter interactively →