DMRTC2

Across TCGA patient cohorts, DMRTC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,625 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DMRTC2-associated GO terms across cancer lineages are DNA replication, Spindle assembly, and Positive regulation of DNA biosynthetic process. Each is linked with DMRTC2 in more than 14 cancer types. Because this analysis shows association rather than direction, both DMRTC2-to-partner and partner-to-DMRTC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by DMRTC2-low versus DMRTC2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRTC2→partner) and Y-score (partner→DMRTC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA replication →	+0.067	+0.122	<.001	<.001	3	15
STAD	Spindle assembly →	+0.067	+0.122	<.001	<.001	3	14
STAD	Positive regulation of DNA biosynthetic process →	+0.114	+0.222	<.001	<.001	3	14
STAD	Peptidyl-lysine modification →	+0.059	+0.163	<.001	<.001	3	14
STAD	Positive regulation of chromosome organization →	+0.098	+0.173	<.001	<.001	3	13
STAD	Mitotic spindle assembly →	+0.072	+0.122	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,625 associations by consensus.

DNA replication by DMRTC2 expression — STAD

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