DMRTC2

Across TCGA cell cohorts, DMRTC2 RNA expression is significantly associated with the mutation status of many other genes, with 149 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DMRTC2-associated genes across cancer lineages are CNTN4, RALGAPA2, and POTEF. Each is linked with DMRTC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DMRTC2-to-partner and partner-to-DMRTC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CNTN4 grouped by DMRTC2-low versus DMRTC2-high in BLOOD_Lymphoma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRTC2→partner) and Y-score (partner→DMRTC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CNTN4 →	+4.058	+0.007	.009	<.001	3	2
BLOOD_Lymphoma	RALGAPA2 →	+4.058	+0.007	.009	<.001	3	2
BLOOD_Lymphoma	POTEF →	+5.643	+0.006	.002	.003	3	2
BLOOD_Leukemia	NRP2 →	+4.539	+0.036	.007	<.001	3	2
OVARY	SNX19 →	+4.700	+0.017	.002	.004	3	2
LUNG_SCLC	SPAG9 →	+4.523	+0.158	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 149 associations by consensus.

CNTN4 by DMRTC2 expression — BLOOD_Lymphoma

Explore this box plot interactively →